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Mon 18 Jun 2007, 13:55 ENL - Enaleni Pharmaceuticals Limited - Dealing in
ENL
 ENL                                                                             
    ENL - Enaleni Pharmaceuticals Limited - Dealing in securities by directors  
                                                                                
    Enaleni Pharmaceuticals Limited                                             
(Incorporated in the Republic of South Africa)                              
    (Registration number 2002/018027/06)                                        
    (JSE code: ENL & ISIN: ZAE000067740)                                        
    ("Enaleni" or "the Company")                                                

    DEALING IN SECURITIES BY DIRECTORS                                          
                                                                                
    In terms of paragraph 3.63 - 3.65 of the JSE Limited Listings Requirements, 
the following information relates to the exercise of share options at a     
    strike price of 100 cents per share and subsequent sale of ordinary shares  
    by directors of Enaleni:                                                    
                                                                                
Executive director:                     T D Edwards                         
    Number of shares:                       116 000                             
    Price per share:                        410 cents per share                 
    Value of transaction:                   R475 600                            
Extent of interest:                     Direct beneficial                   
    Date of transaction:                    15 June 2007                        
    Written clearance to deal obtained:     Yes                                 
                                                                                
Executive director:                     P A Pillay                          
    Number of shares:                       21 000                              
    Price per share:                        410 cents per share                 
    Value of transaction:                   R86 100                             
Extent of interest:                     Direct beneficial                   
    Date of transaction:                    15 June 2007                        
    Written clearance to deal obtained:     Yes                                 
                                                                                
Johannesburg                                                                
    18 June 2007                                                                
                                                                                
    Sponsor                                                                     
Nedbank Capital                                                             
Date: 18/06/2007 13:55:19 Produced by the JSE SENS Department.
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