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Mon 21 Apr 2008, 16:25 ENL - Enaleni Pharmaceuticals Limited - Dealing in
ENL
 ENL                                                                             
ENL - Enaleni Pharmaceuticals Limited - Dealing in securities by directors      
Enaleni Pharmaceuticals Limited                                                 
(Incorporated in the Republic of South Africa)                                  
(Registration number 2002/018027/06)                                            
(JSE code: ENL & ISIN: ZAE000067740)                                            
("Enaleni")                                                                     
DEALING IN SECURITIES BY DIRECTORS                                              
In terms of paragraph 3.63 - 3.65 of the JSE Limited Listings Requirements, the 
following information relates to the dealing in securities by directors of      
Enaleni and its major subsidiary:                                               
Executive director:                     JS Smith                                
Company:                                Enaleni Pharmaceuticals Limited         
Number of shares:                       692 000                                 
Strike price:                           306 cents per share                     
Value of transaction:                   R2 117 520                              
Extent of interest:                     Direct beneficial                       
Date of transaction:                    18 April 2008                           
Nature of transaction:                  Grant and acceptance of share options in
                                       terms of the Enaleni Share Incentive     
Trust                                    
Written clearance to deal obtained:     Yes                                     
Executive director:                     C Aucamp                                
Company:                                Enaleni Pharmaceuticals Limited         
Number of shares:                       217 000                                 
Strike price:                           306 cents per share                     
Value of transaction:                   R664 020                                
Extent of interest:                     Direct beneficial                       
Date of transaction:                    18 April 2008                           
Nature of transaction:                  Grant and acceptance of share options in
                                       terms of the Enaleni Share Incentive     
                                       Trust                                    
Written clearance to deal obtained:     Yes                                     
Executive director:                     AD Watermeyer                           
Company:                                Cipla Medpro Holdings (Proprietary)     
                                       Limited                                  
Number of shares:                       91 000                                  
Strike price:                           306 cents per share                     
Value of transaction:                   R278 460                                
Extent of interest:                     Direct beneficial                       
Date of transaction:                    18 April 2008                           
Nature of transaction:                  Grant and acceptance of share options in
                                       terms of the Enaleni Share Incentive     
                                       Trust                                    
Written clearance to deal obtained:     Yes                                     
Durban                                                                          
21 April 2008                                                                   
Sponsor                                                                         
Nedbank Capital                                                                 
Date: 21/04/2008 16:25:13 Produced by the JSE SENS Department.                  
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