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Alliance - Resignation of Director                                              
ALLIANCE PHARMACEUTICALS LIMITED                                                
(Registration number 1981/006145/06)                                            
Share code: ALN      ISIN code: ZAE000011110                                    
("Alliance" or "the company")                                                   
RESIGNATION OF DIRECTOR                                                         
In compliance with rule 3.67 of the Listings Requirements of the JSE            
Securities Exchange South Africa, Alliance announces the following change to    
the Board of Directors that Dr. HA Serebro has resigned as a director of the    
company with effect from 8 May 2002.                                            
JOHANNESBURG                                                                    
14 May 2002

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