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Wed 1 Sep 2004, 17:36 Director"s Dealings
Alliance - Director`s Dealings                                                  
ALLIANCE PHARMACEUTICALS LIMITED                                                
(Incorporated in the Republic of South Africa)                                  
(Registration number 1981/006145/06)                                            
Share code ALN    ISIN  ZAE000011110                                            
Share code ACN    ISIN  ZAE000011847                                            
(`Alliance`)                                                                    
DIRECTOR`S DEALINGS                                                             
In compliance with paragraph 3.63 to 3.74 of the Listings Requirements of the   
JSE Securities Exchange South Africa (`JSE Listings Requirements`), we hereby   
advise the following dealings by a director in Alliance ordinary shares:        
Director                                :    R Ririe                            
Name of company of which                                                        
he is a director                        :    Alliance                           
Date of transaction                     :    30 August 2004                     
Number of ordinary shares               :    20 000                             
Class                                   :    Ordinary shares                    
Price                                   :    71 cents                           
Total amount                            :    R 14 200                           
Nature                                  :    Sale                               
Extent of interest                      :    Direct beneficial                  
Clearance to deal was obtained in accordance with section 3.66 of the JSE       
Listings Requirements                                                           
1 September 2004
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