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Mon 6 Jun 2005, 16:10 Designated Adviser Dealing In Securities
Enaleni - Designated Adviser Dealing In Securities                              
Enaleni Pharmaceuticals Limited                                                 
(Incorporated in the Republic of South Africa)                                  
(Registration number 2002/018027/06)                                            
JSE Share code: ENL   ISIN: ZAE000067740                                        
(`Enaleni`)                                                                     
Designated Adviser Dealing In Securities                                        
Warning: The listing of ordinary shares in the company is on ALTx.  Investors   
are advised of the risks of investing in a company listed on ALTx. Investors are
advised that the JSE does not guarantee the viability or the success of a       
company listed on ALTx.  In terms of the Listings Requirements, the company is  
obliged to appoint and retain a Designated Adviser, which is required to, inter 
alia, attend all board meetings held by the company to ensure that all the      
Listings Requirements and applicable regulations are complied with, approve the 
Financial Director of the company and guide the company in a competent,         
professional and impartial manner.  If the company fails to retain a Designated 
Adviser, it must make arrangements to appoint a new Designated Adviser within 10
business days, failing which the company faces suspension of trading of its     
securities.  If a Designated Adviser is not appointed within 30 days of its     
suspension, the company faces the termination of its listing without the        
prospect of an appropriate offer to minority shareholders.                      
The JSE has approved the listing of 113 545 024 million shares of Enaleni on    
ALTx with effect from the commencement of business on Friday, 10 June 2005.     
In compliance with rule of 21.30 read with rules 3.63 to 3.65 of the JSE Listing
Requirements, the following should be noted:                                    
Name of person at designated advisor:   M Meyer                                 
Date of transaction:                    6 June 2005                             
Nature of transaction:                  Purchase                                
Price:                                  100 cps                                 
Number of shares:                       215 000                                 
Total amount:                           R 215 000-00                            
Class of security:                      Ordinary Shares                         
Nature of interest:                     Indirect Beneficial                     
Clearance obtained:                     Yes                                     
Name of person at designated advisor:   WP van der Merwe                        
Date of transaction:                    6 June 2005                             
Nature of transaction:                  Purchase                                
Price:                                  100 cps                                 
Number of shares:                       215 000                                 
Total amount:                           R 215 000-00                            
Class of security:                      Ordinary Shares                         
Nature of interest:                     Direct Beneficial                       
Clearance obtained:                     Yes                                     
Name of person at designated advisor:   E Colyn                                 
Date of transaction:                    6 June 2005                             
Nature of transaction:                  Purchase                                
Price:                                  100 cps                                 
Number of shares:                       23 000                                  
Total amount:                           R 23 000-00                             
Class of security:                      Ordinary Shares                         
Nature of interest:                     Direct Beneficial                       
Clearance obtained:                     Yes                                     
6 June 2005                                                                     
Durban                                                                          
Date: 06/06/2005 03:58:07 PM
Produced by the JSE SENS Department                                             
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