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Fri 23 Sep 2005, 9:03 Aspen and India's Matrix sign JVs
Aspen and India`s Matrix sign JVs                                               
Aspen Pharmacare Holdings Limited                                               
(Incorporated in the Republic of South Africa)                                  
(Registration number 1985/002935/06)                                            
Share code:  APN   ISIN: ZAE000066692                                           
Press Release                                                                   
26 September 2005                                                               
Aspen and India`s Matrix sign JVs                                               
Aspen Pharmacare Holdings Limited (Aspen) has signed definitive joint venture   
(JV) agreements with Indian-based Matrix Laboratories Limited (Matrix). The     
deals strengthen Aspen`s vertical integration into the manufacture of Active    
Pharmaceutical Ingredients (APIs), the key raw materials required in the        
manufacture of finished dosage form pharmaceuticals including anti-retrovirals  
(ARVs), and they unlock additional global supply and manufacturing              
opportunities.                                                                  
The basis of the two JVs is:                                                    
The sale of 50% of Aspen`s 100% ownership of Cape Town based Fine Chemicals     
Corporation (Pty) Ltd (FCC) to Matrix for a purchase consideration of US$       
20million.  FCC is South Africa`s leading API manufacturer and a major exporter 
of product to the USA and other territories;                                    
Aspen to acquire a 50% stake of a newly incorporated Indian company, Astrix     
Laboratories (`Astrix`), into which Matrix will transfer an API manufacturing   
facility, technology and intellectual property (IP) for a consideration of      
US$36,5 million                                                                 
Stephen Saad, Aspen`s Group Chief Executive said `the JVs strengthen Aspen`s    
supply source for APIs to meet the increasing demand for pharmaceutical         
products, most notably ARVs. The deals also provide for additional global       
trading opportunities for Aspen. Matrix`s technological expertise complements   
Aspen`s successful strategy of manufacturing quality, internationally approved  
medicines, including ARVs. The finished dosage form products for which the APIs 
are required will be manufactured at Aspen`s US Food and Drug Administration    
(FDA) and World Health Organisation (WHO) accredited Oral Solid Dose (OSD)      
facility in Port Elizabeth`.                                                    
Saad added that he expected Astrix to record revenue in the order of $40 million
in its first full year of operation and that Aspen would be a material customer.
N Prasad, Executive Chairman of Matrix said `the long-term strategic            
relationship between Matrix and Aspen is a great leap forward. It will result in
combining the strengths of both the companies to achieve global leadership      
positions by meeting the large unfulfilled needs in the treatment of HIV/AIDS.  
This alliance also gives Matrix a strategic presence in South Africa.           
Technological expertise provided by Matrix will assist in unlocking additional  
value in the FCC business.`                                                     
The Astrix facility, situated near Hyderabad, will be Aspen`s lead supplier of  
ARV APIs. Astrix will also continue supplying its existing customer base with   
ARV APIs.  The site offers scope for modular expansion and in terms of the      
agreement Astrix may also source additional API volumes from other Matrix       
production facilities on a toll-manufacture basis.                              
Approvals for the JVs are subject to approvals by, inter alia,  the South       
African Reserve Bank, the Reserve Bank of India and South Africa`s Competition  
authorities.                                                                    
JSE listed Aspen is the southern hemisphere`s largest generic pharmaceutical    
manufacturer and a global leader in generic ARVs.  Matrix is a leading          
international API manufacturer listed on the National and Bombay Stock          
Exchanges.                                                                      
The US FDA`s 2004 accreditation of Aspen`s world class OSD facility and         
registration of its co-pack triple combination generic ARV treatment qualified  
Aspen as the first generic supplier under President Bush`s Emergency Plan for   
AIDS relief (PEPFAR) programme to which funding of US$15 billion has been       
committed.                                                                      
Aspen has actively pursued a meaningful solution to the provision of high       
quality, affordable generic ARVs in the fight against HIV/Aids. Aspen pioneered 
the conclusion of voluntary licence agreements with leading multinationals for  
the manufacture of generic ARVs which were developed in Aspen`s own             
laboratories. This underscores Aspen`s scientific and technical capabilities,   
its manufacturing and quality standards, and GMP compliances. Aspen was also    
recently awarded the lion`s share of the South African government`s ARV tender. 
ends                                                                            
Issued by:               Shauneen Beukes, Shauneen Beukes Communications        
                    Tel: (012) 661-8467                                         
                    Fax: (088) (012) 6618467                                    
Cell: 082 389 8900                                                              
On Behalf Of:       Stephen Saad, Aspen Holdings Group CEO                      
                    Tel: (031) 580-8602                                         
                    Fax: (031) 580-8640                                         
                    Cell:  083 303 4833                                         
Gus Attridge, Aspen Holdings Deputy Group CEO               
                    Tel: (031) 580-8604                                         
                    Fax: (031) 580-8640                                         
                    Cell: 083 628 8813                                          
Date: 23/09/2005 09:00:15 AM
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