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Tue 25 Oct 2005, 17:00 Enaleni Pharmaceuticals Limited - Directors Dealin
Enaleni Pharmaceuticals Limited - Director"s Dealing In Securities              
ENALENI PHARMACEUTICALS LIMITED                                                 
(Incorporated in the Republic of South Africa)                                  
(Registration number 2002/018027/06)                                            
JSE Share code: ENL   ISIN: ZAE000067740                                        
("Enaleni")                                                                     
Directors Dealing In Securities                                                 
Warning: The listing of ordinary shares in the company is on ALTx.  Investors   
are advised of the risks of investing in a company listed on ALTx. Investors are
advised that the JSE does not guarantee the viability or the success of a       
company listed on ALTx.  In terms of the Listings Requirements, the company is  
obliged to appoint and retain a Designated Adviser, which is required to, inter 
alia, attend all board meetings held by the company to ensure that all the      
Listings Requirements and applicable regulations are complied with, approve the 
Financial Director of the company and guide the company in a competent,         
professional and impartial manner.  If the company fails to retain a Designated 
Adviser, it must make arrangements to appoint a new Designated Adviser within 10
business days, failing which the company faces suspension of trading of its     
securities.  If a Designated Adviser is not appointed within 30 days of its     
suspension, the company faces the termination of its listing without the        
prospect of an appropriate offer to minority shareholders.                      
In compliance with rule of 3.63 to 3.74 of the JSE Listing Requirements, the    
following should be noted:                                                      
Name of director:             DDT Tambo                                         
Date of transaction:          24 October 2005                                   
Nature of transaction:        Sale                                              
Price:                        354 cps                                           
Number of shares:             180 000                                           
Total amount:                 R 637 200                                         
Class of security:            Ordinary Shares                                   
Nature of interest:           Indirect Beneficial                               
Clearance obtained:           Yes                                               
25 October 2005                                                                 
Durban                                                                          
Designated Advisor                                                              
Exchange Sponsors (Pty) Ltd                                                     
Date: 25/10/2005 05:00:12 PM Produced by the JSE SENS Department                
                                                                                
                                                                                
                                                                                
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