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Fri 28 Oct 2005, 15:54 Enaleni - Directors dealing in securities
Enaleni - Directors dealing in securities                                       
ENALENI PHARMACEUTICALS LIMITED                                                 
(Incorporated in the Republic of South Africa)                                  
(Registration number 2002/018027/06)                                            
JSE Share code: ENL & ISIN: ZAE000067740                                        
("Enaleni")                                                                     
Directors dealing in securities                                                 
Warning: The listing of ordinary shares in the company is on ALTx.  Investors   
are advised of the risks of investing in a company listed on ALTx. Investors are
advised that the JSE does not guarantee the viability or the success of a       
company listed on ALTx.  In terms of the Listings Requirements, the company is  
obliged to appoint and retain a Designated Adviser, which is required to, inter 
alia, attend all board meetings held by the company to ensure that all the      
Listings Requirements and applicable regulations are complied with, approve the 
Financial Director of the company and guide the company in a competent,         
professional and impartial manner.  If the company fails to retain a Designated 
Adviser, it must make arrangements to appoint a new Designated Adviser within 10
business days, failing which the company faces suspension of trading of its     
securities.  If a Designated Adviser is not appointed within 30 days of its     
suspension, the company faces the termination of its listing without the        
prospect of an appropriate offer to minority shareholders.                      
In compliance with rule of 3.63 to 3.65 of the JSE Listing Requirements, the    
following should be noted:                                                      
Name of director:        DDT Tambo                                              
Date of transaction:     27 October 2005                                        
Nature of transaction:   Sale                                                   
Price:                   293 cps                                                
Number of shares:        299 500                                                
Total amount:            R 878 684                                              
Class of security:       Ordinary Shares                                        
Nature of interest:      Indirect Beneficial                                    
Clearance obtained:      Yes                                                    
28 October 2005                                                                 
Johannesburg                                                                    
Designated Advisor:                                                             
Exchange Sponsors (Pty) Ltd                                                     
Date: 28/10/2005 03:54:04 PM Produced by the JSE SENS Department                
                                                                                
                                                                                
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