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APN
 APN                                                                             
Aspen Pharmacare Holdings Limited - Cautionary announcement                     
Aspen Pharmacare Holdings Limited                                               
(Incorporated in the Republic of South Africa)                                  
(Registration number 1985/002935/06)                                            
Share code:  APN & ISIN: ZAE000066692                                           
("the company")                                                                 
Cautionary announcement                                                         
Shareholders of the company are advised that the company has entered into       
acquisition negotiations, which, if successfully concluded, may have a material 
effect on the price at which the company"s securities trade on the JSE Limited. 
Accordingly, shareholders of the company are advised to exercise caution when   
dealing in the company"s securities until a further announcement is made.       
Johannesburg                                                                    
31 May 2006                                                                     
Sponsor                                                                         
Investec Bank Limited                                                           
Date: 31/05/2006 03:50:03 PM Produced by the JSE SENS Department                
                                                                                
                                                                                

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