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Fri 11 Aug 2006, 12:16 Enaleni Pharmaceuticals Limited - Trading update
ENL
 ENL                                                                             
Enaleni Pharmaceuticals Limited - Trading update                                
Enaleni Pharmaceuticals Limited                                                 
(Incorporated in the Republic of South Africa)                                  
(Registration number 2002/018027/06)                                            
(JSE code: ENL & ISIN: ZAE000067740)                                            
("Enaleni")                                                                     
Trading update                                                                  
Shareholders are referred to the circular dated 28 November 2005, which         
contained the results for the six month period ended 30 June 2005, wherein      
earnings per share ("EPS") was disclosed as 8.7 cents and headline earnings per 
share ("HEPS") was disclosed as 4.3 cents. Shareholders are now advised that it 
is expected that EPS for the period ended 30 June 2006 will be 45% - 55% higher 
than the figures disclosed in the circular for the prior comparative period and 
HEPS is expected to be 185% - 195% higher than the figures for the prior        
comparative period.                                                             
The above information has not been reviewed by the company"s auditors and the   
company"s interim results for the six months ended 30 June 2006 are expected to 
be published on 28 August 2006.                                                 
11 August 2006                                                                  
Sponsor                                                                         
Nedbank Capital                                                                 
Date: 11/08/2006 12:16:02 PM Produced by the JSE SENS Department                
                                                                                
                                                                                
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